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Approved Drugs
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Inhibitors
Name:  1-[4-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C29H33N9O3
Similarity:  0.875
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[(3R)-3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C31H38N10O2
Similarity:  0.8283582089552238
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[(3R)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C31H36N10O3
Similarity:  0.8161764705882353
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[(3S)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C31H36N10O3
Similarity:  0.8161764705882353
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[4-[[5-[6-(methylamino)-2-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C30H34N8O3
Similarity:  0.7518248175182481
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[4-[[5-[5-(methylamino)-3-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C30H34N8O3
Similarity:  0.7266187050359713
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C31H36N10O3
Similarity:  0.7152777777777778
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[4-[[5-[2-(methylamino)-4-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C30H34N8O3
Similarity:  0.7021276595744681
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[4-[[2-[4-(4-but-3-ynylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C33H38N10O2
Similarity:  0.6959459459459459
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[(2S)-2-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one
Formula:  C31H36N10O3
Similarity:  0.668918918918919
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[(2R)-2-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one
Formula:  C31H36N10O3
Similarity:  0.668918918918919
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C32H32N10O3
Similarity:  0.5625
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[4-[2-(4-morpholinoanilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula:  C24H27N5O3S
Similarity:  0.5390070921985816
Relative Targets:   Epidermal growth factor receptor  |