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Approved Drugs

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Inhibitors

Name:  1-[(2R)-2-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C31H36N10O3

Similarity:  1.0

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3R)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C31H36N10O3

Similarity:  0.8142857142857143

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3S)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C31H36N10O3

Similarity:  0.8142857142857143

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C31H36N10O3

Similarity:  0.7887323943661971

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3R)-3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C31H38N10O2

Similarity:  0.726027397260274

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3R)-3-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C29H33N9O3

Similarity:  0.668918918918919

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C32H32N10O3

Similarity:  0.6688311688311688

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[2-[4-(4-but-3-ynylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C33H38N10O2

Similarity:  0.6645161290322581

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C29H33N9O3

Similarity:  0.6577181208053692

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[6-(methylamino)-2-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C30H34N8O3

Similarity:  0.5632911392405063

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[5-(methylamino)-3-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C30H34N8O3

Similarity:  0.54375

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[2-(methylamino)-4-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C30H34N8O3

Similarity:  0.5246913580246914

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |