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Name:  1-[(3R)-3-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₂₉H₃₃N₉O₃

Similarity:  0.875

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[6-(methylamino)-2-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₀H₃₄N₈O₃

Similarity:  0.8604651162790697

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[5-(methylamino)-3-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₀H₃₄N₈O₃

Similarity:  0.8320610687022901

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.8161764705882353

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[2-(methylamino)-4-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₀H₃₄N₈O₃

Similarity:  0.8045112781954887

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[2-[4-(4-but-3-ynylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₃H₃₈N₁₀O₂

Similarity:  0.7928571428571428

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3R)-3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₁H₃₈N₁₀O₂

Similarity:  0.7375886524822695

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3R)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.7272727272727273

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3S)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.7272727272727273

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(2S)-2-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.6577181208053692

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(2R)-2-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.6577181208053692

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[2-(4-morpholinoanilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C24H27N5O3S

Similarity:  0.631578947368421

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H31N7O2

Similarity:  0.5755395683453237

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C₃₂H₃₂N₁₀O₃

Similarity:  0.5723270440251572

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H30N6O2S

Similarity:  0.5314685314685315

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-(2-methoxy-4-morpholino-anilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H29N5O4S

Similarity:  0.5310344827586206

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C23H29ClN6O2

Similarity:  0.5251798561151079

Relative Targets:   Epidermal growth factor receptor  |