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Approved Drugs
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.592
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.5511811023622047
Inhibitors
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H27ClFN5O3
Similarity: 0.8504672897196262
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-propoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C25H29ClFN5O3
Similarity: 0.7946428571428571
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C23H25ClFN5O3
Similarity: 0.7567567567567568
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-methoxypropoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H27ClFN5O3
Similarity: 0.7368421052631579
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-isopropoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C25H29ClFN5O3
Similarity: 0.7241379310344828
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C25H27ClFN5O3
Similarity: 0.7033898305084746
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C24H25ClFN5O2
Similarity: 0.6810344827586207
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-[2-(4-hydroxybutoxy)ethoxy]quinazolin-6-yl]prop-2-enamide
Formula: C23H24ClFN4O4
Similarity: 0.6610169491525424
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C31H33ClFN5O4
Similarity: 0.6567164179104478
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula: C27H29ClFN5O3
Similarity: 0.656
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H25FN6O3
Similarity: 0.65
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1R)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H27ClFN5O3
Similarity: 0.6416666666666667
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1S)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H27ClFN5O3
Similarity: 0.6416666666666667
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C23H23ClFN5O2
Similarity: 0.635593220338983
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula: C26H27ClFN5O2
Similarity: 0.6341463414634146
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H25ClF3N5O3
Similarity: 0.6290322580645161
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-(diethylamino)but-2-enamide
Formula: C25H25ClFN5O2
Similarity: 0.628099173553719
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C23H23ClFN5O2
Similarity: 0.6271186440677966
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C26H29ClFN5O3
Similarity: 0.6220472440944882
Relative Targets: Epidermal growth factor receptor |