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Approved Drugs
Inhibitors
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H27ClFN5O3
Similarity:  0.9117647058823529
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C23H25ClFN5O3
Similarity:  0.8640776699029126
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-methoxypropoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H27ClFN5O3
Similarity:  0.839622641509434
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-isopropoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C25H29ClFN5O3
Similarity:  0.8240740740740741
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(diethylamino)but-2-enamide
Formula:  C26H31ClFN5O3
Similarity:  0.7946428571428571
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H25FN6O3
Similarity:  0.7410714285714286
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.7368421052631579
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1R)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H27ClFN5O3
Similarity:  0.7321428571428571
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1S)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H27ClFN5O3
Similarity:  0.7321428571428571
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H25ClF3N5O3
Similarity:  0.7155172413793104
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C24H25ClFN5O2
Similarity:  0.6991150442477876
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C31H33ClFN5O4
Similarity:  0.6976744186046512
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[2-(4-hydroxybutoxy)ethoxy]quinazolin-6-yl]prop-2-enamide
Formula:  C23H24ClFN4O4
Similarity:  0.6929824561403509
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(4-bromo-2-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C23H25BrFN5O3
Similarity:  0.6842105263157895
Relative Targets:   Epidermal growth factor receptor  |
Name:  Afatinib
Formula:  C24H25ClFN5O3
Similarity:  0.6752136752136753
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula:  C27H29ClFN5O3
Similarity:  0.6721311475409836
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide
Formula:  C25H27N5O3
Similarity:  0.6637931034482759
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C30H31ClFN5O4
Similarity:  0.6615384615384615
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C23H23ClFN5O2
Similarity:  0.6578947368421053
Relative Targets:   Epidermal growth factor receptor  |