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Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6991150442477876

Name:  Dacomitinib

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.5966386554621849

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1S)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₇ClFN₅O₃

Similarity:  1.0

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₃H₂₅ClFN₅O₃

Similarity:  0.8076923076923077

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-isopropoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₅H₂₉ClFN₅O₃

Similarity:  0.7870370370370371

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-methoxypropoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₇ClFN₅O₃

Similarity:  0.7850467289719626

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₇ClFN₅O₃

Similarity:  0.7522935779816514

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-propoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₅H₂₉ClFN₅O₃

Similarity:  0.7321428571428571

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(diisopropylamino)but-2-enamide

Formula:  C₂₅H₂₉ClFN₅O₂

Similarity:  0.7181818181818181

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6991150442477876

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C₂₃H₂₃ClFN₅O₂

Similarity:  0.6972477064220184

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₅FN₆O₃

Similarity:  0.6902654867256637

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C₂₅H₂₇ClFN₅O₃

Similarity:  0.6869565217391305

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.6785714285714286

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6695652173913044

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₅ClF₃N₅O₃

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₁H₂₀ClF₂N₅O₂

Similarity:  0.6605504587155964

Relative Targets:   Tyrosine-protein kinase JAK2  | Epidermal growth factor receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor alpha  | Fibroblast growth factor receptor 2  | RAC-beta serine/threonine-protein kinase  | Potassium voltage-gated channel subfamily H member 2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₁₉H₁₈ClFN₆O

Similarity:  0.6571428571428571

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(diethylamino)but-2-enamide

Formula:  C₂₆H₃₁ClFN₅O₃

Similarity:  0.6416666666666667

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(4-bromo-2-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₃H₂₅BrFN₅O₃

Similarity:  0.6347826086956522

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide

Formula:  C₂₂H₂₁ClFN₅O₂

Similarity:  0.6339285714285714

Relative Targets:   Epidermal growth factor receptor  |