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Approved Drugs
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Inhibitors
Name:  N-[3-[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-5-isopropyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C30H36N8O4
Similarity:  0.8253968253968254
Relative Targets:   Epidermal growth factor receptor  |
Name:  Egfr-IN-1
Formula:  C28H30N6O4
Similarity:  0.7401574803149606
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[3-[5-isopropyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C30H34N8O4
Similarity:  0.6934306569343066
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-isopropyl-2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C30H34N8O4
Similarity:  0.6338028169014085
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-[2-(Dimethylamino)ethyl-methylamino]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H33N7O3
Similarity:  0.6159420289855072
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-isopropyl-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C35H43N9O4
Similarity:  0.6129032258064516
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C28H30N8O4
Similarity:  0.5985915492957746
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-ethyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C29H32N8O4
Similarity:  0.5972222222222222
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-5-propyl-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C30H34N8O4
Similarity:  0.5958904109589042
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-isopropyl-2-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C30H34N8O3
Similarity:  0.5902777777777778
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[6-isopropyl-2-[4-(2-methoxyethoxy)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N6O4
Similarity:  0.5531914893617021
Relative Targets:   Tyrosine-protein kinase BTK  |
Name:  N-[3-[2-[4-(2-methoxyethoxy)anilino]-7-methyl-8-oxo-purin-9-yl]phenyl]prop-2-enamide
Formula:  C24H24N6O4
Similarity:  0.5514705882352942
Relative Targets:   Tyrosine-protein kinase BTK  |
Name:  N-[3-[7-[4-(dimethylamino)-2-methoxy-anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C25H27N7O3
Similarity:  0.5474452554744526
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-5H-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N8O4
Similarity:  0.541095890410959
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C29H33N7O3
Similarity:  0.5342465753424658
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[4-(2-methoxyethoxy)anilino]-6-methyl-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C25H24N6O4
Similarity:  0.5285714285714286
Relative Targets:   Tyrosine-protein kinase BTK  |
Name:  N-[3-[6-tert-butyl-2-[4-(2-methoxyethoxy)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C28H30N6O4
Similarity:  0.5241379310344828
Relative Targets:   Tyrosine-protein kinase BTK  |
Name:  N-[3-[7-(2-methoxyethyl)-2-[(6-methoxy-3-pyridyl)amino]-8-oxo-purin-9-yl]phenyl]prop-2-enamide
Formula:  C23H23N7O4
Similarity:  0.5179856115107914
Relative Targets:   Tyrosine-protein kinase BTK  |
Name:  N-[3-[6-ethyl-2-[4-(2-methoxyethoxy)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C26H26N6O4
Similarity:  0.5174825174825175
Relative Targets:   Tyrosine-protein kinase BTK  |