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Approved Drugs
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 1.0
Name: Zanubrutinib
Formula: C27H29N5O3
Similarity: 0.5271317829457365
Inhibitors
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 1.0
Relative Targets: Epidermal growth factor receptor | Tyrosine-protein kinase Lyn | Cytoplasmic tyrosine-protein kinase BMX | Tyrosine-protein kinase JAK3 | Tyrosine-protein kinase BTK | Potassium voltage-gated channel subfamily H member 2 | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C24H22N6O2
Similarity: 0.9285714285714286
Relative Targets: Epidermal growth factor receptor |
Name: (E)-1-[3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-chloro-prop-2-en-1-one
Formula: C25H23ClN6O2
Similarity: 0.875
Relative Targets: Tyrosine-protein kinase BTK |
Name: (E)-1-[3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]but-2-en-1-one
Formula: C26H26N6O2
Similarity: 0.875
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[(3R)-3-[4-amino-3-(4-benzyloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H26N6O2
Similarity: 0.839622641509434
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3S)-3-[4-amino-3-(2-methyl-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H26N6O2
Similarity: 0.7962962962962963
Relative Targets: Tyrosine-protein kinase BTK |
Name: (E)-2-[(3S)-3-(4-amino-3-phenyl-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl]-3-cyclopropyl-prop-2-enenitrile
Formula: C30H31N7O2
Similarity: 0.7542372881355932
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-(4-amino-3-phenyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O
Similarity: 0.7448979591836735
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(2-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H22N6O
Similarity: 0.7264150943396226
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3S)-3-[4-amino-3-(2,6-dimethyl-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C27H28N6O2
Similarity: 0.7192982456140351
Relative Targets: Tyrosine-protein kinase BTK |
Name: 6-Amino-7-(4-phenoxyphenyl)-9-[(3R)-1-prop-2-enoylpiperidin-3-yl]purin-8-one
Formula: C25H24N6O3
Similarity: 0.7017543859649122
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[(3R)-3-[4-amino-3-(4-benzyloxy-3-chloro-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H25ClN6O2
Similarity: 0.6982758620689655
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H19FN6O
Similarity: 0.696078431372549
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O2
Similarity: 0.696078431372549
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H22N6O
Similarity: 0.6944444444444444
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 3-(4-phenoxyphenyl)-1-[(3R)-1-prop-2-enoyl-3-piperidyl]pyrazole-4-carboxamide
Formula: C24H24N4O3
Similarity: 0.6666666666666666
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[3-[5-(hydroxymethyl)-3-(4-phenoxyphenyl)pyrazol-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C24H25N3O3
Similarity: 0.6636363636363637
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[(3R)-3-[4-amino-3-(4-fluoro-1-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H21FN6O
Similarity: 0.6517857142857143
Relative Targets: Epidermal growth factor receptor |
Name: 5-(4-phenoxyphenyl)-2-(1-prop-2-enoyl-3-piperidyl)pyrazole-3-carboxylic acid
Formula: C24H23N3O4
Similarity: 0.6517857142857143
Relative Targets: Tyrosine-protein kinase BTK |