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Approved Drugs

Name:  Zanubrutinib

Formula:  C27H29N5O3

Similarity:  0.6440677966101694

Inhibitors

Name:  2-(4-phenoxyphenyl)-7-(prop-2-enoylamino)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H21N5O3

Similarity:  0.79

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[1-(prop-2-enoylamino)cyclopropyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H25N5O3

Similarity:  0.7314814814814815

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(1-prop-2-enoylazetidin-3-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H25N5O3

Similarity:  0.6846846846846847

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[3-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H25N5O3

Similarity:  0.6694915254237288

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[4-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H25N5O3

Similarity:  0.6694915254237288

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H25N5O3

Similarity:  0.6694915254237288

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O3

Similarity:  0.6440677966101694

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (7S)-2-(4-phenoxyphenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O3

Similarity:  0.6440677966101694

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-[methyl(prop-2-enoyl)amino]phenyl]-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C29H27N5O3

Similarity:  0.6311475409836066

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxyphenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H23N5O3

Similarity:  0.6306306306306306

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-(prop-2-enoylamino)phenyl]-2-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H20F3N5O3

Similarity:  0.5932203389830508

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-(prop-2-enoylamino)phenyl]-2-(p-tolyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H23N5O2

Similarity:  0.5892857142857143

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (7S)-7-(1-but-2-ynoyl-4-piperidyl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H29N5O3

Similarity:  0.5887096774193549

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[4-(2-methoxyethoxy)phenyl]-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H27N5O4

Similarity:  0.5833333333333334

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-chlorophenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H20ClN5O2

Similarity:  0.5752212389380531

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-fluorophenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H20FN5O2

Similarity:  0.5752212389380531

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[4-(cyclopropylmethoxy)phenyl]-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C26H27N5O3

Similarity:  0.5702479338842975

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-(prop-2-enoylamino)phenyl]-2-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H20F3N5O2

Similarity:  0.5546218487394958

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  6-(4-phenoxyphenyl)-2-(1-prop-2-enoylpyrrolidin-3-yl)-1H-imidazo[1,2-b]pyrazole-7-carboxamide

Formula:  C25H23N5O3

Similarity:  0.5537190082644629

Relative Targets:   Tyrosine-protein kinase BTK  |