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Approved Drugs

Name:  Zanubrutinib

Formula:  C27H29N5O3

Similarity:  0.5076923076923077

Inhibitors

Name:  7-[2-(prop-2-enoylamino)phenyl]-2-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H20F3N5O2

Similarity:  0.8514851485148515

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxyphenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H23N5O3

Similarity:  0.83

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-fluorophenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H20FN5O2

Similarity:  0.8

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-(prop-2-enoylamino)phenyl]-2-(p-tolyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H23N5O2

Similarity:  0.7821782178217822

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-chlorophenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H20ClN5O2

Similarity:  0.7821782178217822

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[4-(cyclopropylmethoxy)phenyl]-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C26H27N5O3

Similarity:  0.7614678899082569

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[4-(2-methoxyethoxy)phenyl]-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H27N5O4

Similarity:  0.7614678899082569

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[4-(cyclopentoxy)phenyl]-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O3

Similarity:  0.7345132743362832

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H25N5O3

Similarity:  0.7155172413793104

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(prop-2-enoylamino)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H21N5O3

Similarity:  0.6160714285714286

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[3-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H25N5O3

Similarity:  0.6048387096774194

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[4-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H25N5O3

Similarity:  0.6048387096774194

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(3,5-dimethoxy-4-methyl-phenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H27N5O4

Similarity:  0.5966386554621849

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[1-methyl-1-(prop-2-enoylamino)ethyl]-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H27N5O3

Similarity:  0.5932203389830508

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[1-(prop-2-enoylamino)cyclopropyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H25N5O3

Similarity:  0.575

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-[methyl(prop-2-enoyl)amino]phenyl]-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C29H27N5O3

Similarity:  0.5703125

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-cyclopropyl-3,5-dimethoxy-phenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O4

Similarity:  0.568

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(1-prop-2-enoylazetidin-3-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H25N5O3

Similarity:  0.5365853658536586

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O3

Similarity:  0.5076923076923077

Relative Targets:   Tyrosine-protein kinase BTK  |