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Approved Drugs

Name:  Zanubrutinib

Formula:  C27H29N5O3

Similarity:  0.5590551181102362

Inhibitors

Name:  2-(4-methoxyphenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H23N5O3

Similarity:  0.8137254901960784

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[4-(cyclopentoxy)phenyl]-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O3

Similarity:  0.8

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[4-(2-methoxyethoxy)phenyl]-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H27N5O4

Similarity:  0.7962962962962963

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-(prop-2-enoylamino)phenyl]-2-(p-tolyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H23N5O2

Similarity:  0.7669902912621359

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-chlorophenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H20ClN5O2

Similarity:  0.7669902912621359

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-fluorophenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H20FN5O2

Similarity:  0.7669902912621359

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-(prop-2-enoylamino)phenyl]-2-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H20F3N5O3

Similarity:  0.7614678899082569

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-(prop-2-enoylamino)phenyl]-2-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H20F3N5O2

Similarity:  0.7181818181818181

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H25N5O3

Similarity:  0.7033898305084746

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-cyclopropyl-3,5-dimethoxy-phenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O4

Similarity:  0.6229508196721312

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(prop-2-enoylamino)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H21N5O3

Similarity:  0.6052631578947368

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[3-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H25N5O3

Similarity:  0.5952380952380952

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[4-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H25N5O3

Similarity:  0.5952380952380952

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-[1-(prop-2-enoylamino)cyclopropyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H25N5O3

Similarity:  0.5916666666666667

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(3,5-dimethoxy-4-methyl-phenyl)-7-[2-(prop-2-enoylamino)phenyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H27N5O4

Similarity:  0.5867768595041323

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[1-methyl-1-(prop-2-enoylamino)ethyl]-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H27N5O3

Similarity:  0.5702479338842975

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(1-prop-2-enoylazetidin-3-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H25N5O3

Similarity:  0.5655737704918032

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-[methyl(prop-2-enoyl)amino]phenyl]-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C29H27N5O3

Similarity:  0.5615384615384615

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O3

Similarity:  0.5590551181102362

Relative Targets:   Tyrosine-protein kinase BTK  |