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Inhibitors

Name:  N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-4-[[(Z)-4-(dimethylamino)but-2-enoyl]amino]benzamide

Formula:  C31H28ClN7O2

Similarity:  0.7727272727272727

Relative Targets:   Cyclin-dependent kinase 7  |

Name:  4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[[6-(4-phenylphenyl)pyrimidin-4-yl]amino]phenyl]benzamide

Formula:  C35H32N6O2

Similarity:  0.7338129496402878

Relative Targets:   Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha  |

Name:  4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[[6-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrimidin-4-yl]amino]phenyl]benzamide

Formula:  C30H28N8O2

Similarity:  0.7313432835820896

Relative Targets:   Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha  |

Name:  4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[[6-(2-methylindazol-5-yl)pyrimidin-4-yl]amino]phenyl]benzamide

Formula:  C31H30N8O2

Similarity:  0.708029197080292

Relative Targets:   Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha  |

Name:  4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[[4-(4-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide

Formula:  C32H31N7O2

Similarity:  0.6956521739130435

Relative Targets:   Serine/threonine-protein kinase N3  |

Name:  4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[[6-(4-methylanilino)pyrimidin-4-yl]amino]phenyl]benzamide

Formula:  C30H31N7O2

Similarity:  0.6888888888888889

Relative Targets:   Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha  |

Name:  4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[[6-(4-phenylanilino)pyrimidin-4-yl]amino]phenyl]benzamide

Formula:  C35H33N7O2

Similarity:  0.6827586206896552

Relative Targets:   Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha  |

Name:  4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[[6-(3-phenylanilino)pyrimidin-4-yl]amino]phenyl]benzamide

Formula:  C35H33N7O2

Similarity:  0.6827586206896552

Relative Targets:   Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha  |

Name:  4-[[6-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-4-quinolyl]oxy]-N-(2-pyridyl)benzamide

Formula:  C27H25N5O3

Similarity:  0.5390070921985816

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexyl]-4-[[(Z)-4-(dimethylamino)but-2-enoyl]amino]benzamide

Formula:  C31H34ClN7O2

Similarity:  0.5294117647058824

Relative Targets:   Cyclin-dependent kinase 7  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]pyrrolidine-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C29H30ClN7O2

Similarity:  0.52

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-methyl-4-[[4-(3-pyridyl)pyrimidin-2-yl]amino]phenyl]benzamide

Formula:  C29H29N7O2

Similarity:  0.5100671140939598

Relative Targets:   Mitogen-activated protein kinase 8  | Mitogen-activated protein kinase 9  | Mitogen-activated protein kinase 10  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H32ClN7O2

Similarity:  0.5098039215686274

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(3R)-3-[[5-bromo-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H32BrN7O2

Similarity:  0.5098039215686274

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  N-[2-[3-[[(E)-4-(Dimethylamino)but-2-enoyl]amino]anilino]pyrimidin-5-yl]-2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]benzamide

Formula:  C32H30F3N7O3

Similarity:  0.5031055900621118

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-N-[3-[[5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxyphenyl]-4-(dimethylamino)but-2-enamide

Formula:  C25H25ClN6O2

Similarity:  0.5

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]azepane-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C31H34ClN7O2

Similarity:  0.5

Relative Targets:   Cyclin-dependent kinase 12  |