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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5072463768115942

Inhibitors

Name:  N-[3-[[2-[4-[4-(2-fluoroethyl)piperazin-1-yl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C27H31FN8O3

Similarity:  0.847457627118644

Relative Targets:   Epidermal growth factor receptor  |

Name:  N1'-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-N1-[3-(prop-2-enoylamino)phenyl]cyclopropane-1,1-dicarboxamide

Formula:  C30H34N8O4

Similarity:  0.8292682926829268

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C25H27N7O4

Similarity:  0.8260869565217391

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C31H39N9O3

Similarity:  0.8253968253968254

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C27H30N8O4

Similarity:  0.8235294117647058

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-methyl-carbamoyl]amino]phenyl]prop-2-enamide

Formula:  C27H32N8O3

Similarity:  0.8135593220338984

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-2-methyl-N-[3-(prop-2-enoylamino)phenyl]propanamide

Formula:  C29H35N7O3

Similarity:  0.8

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[4-(dimethylamino)-1-piperidyl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C28H34N8O3

Similarity:  0.7933884297520661

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C25H28N8O2

Similarity:  0.7844827586206896

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C27H31N7O3

Similarity:  0.7815126050420168

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[4-(diethylamino)-1-piperidyl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C30H38N8O3

Similarity:  0.7559055118110236

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C30H36N8O4

Similarity:  0.7538461538461538

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(2,4-dimethoxyanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C22H22N6O4

Similarity:  0.7280701754385965

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C25H28ClN7O2

Similarity:  0.7166666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(morpholine-4-carbonyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H27N7O5

Similarity:  0.7063492063492064

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(2-methoxyanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C21H20N6O3

Similarity:  0.6842105263157895

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(diethylamino)-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C25H29N7O3

Similarity:  0.680327868852459

Relative Targets:   Epidermal growth factor receptor  |

Name:  WZ4002

Formula:  C25H27ClN6O3

Similarity:  0.6612903225806451

Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C25H27ClN6O2S

Similarity:  0.6612903225806451

Relative Targets:   Epidermal growth factor receptor  |