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Approved Drugs

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Inhibitors

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C25H28N8O2

Similarity:  0.8181818181818182

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C25H27N7O4

Similarity:  0.7807017543859649

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.7476635514018691

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-(1-methyl-4-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H29N7O2

Similarity:  0.7241379310344828

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(dimethylamino)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C22H23N7O2

Similarity:  0.7

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[5-methylsulfanyl-2-(4-morpholinoanilino)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26N6O2S

Similarity:  0.6810344827586207

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6696428571428571

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  methyl-[2-(4-morpholinoanilino)-4-[3-(prop-2-enoylamino)anilino]pyrimidin-5-yl]-oxido-sulfonium

Formula:  C24H26N6O3S

Similarity:  0.6694915254237288

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[[2-[2-methoxy-4-(morpholine-4-carbonyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H27N7O5

Similarity:  0.664

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(2-methoxyethoxy)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C23H24N6O4

Similarity:  0.6581196581196581

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.6521739130434783

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C30H36N8O4

Similarity:  0.6492537313432836

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6403508771929824

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H30N8O3

Similarity:  0.64

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6386554621848739

Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.6209677419354839

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[4-(dimethylamino)-1-piperidyl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C28H34N8O3

Similarity:  0.6153846153846154

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-(4-morpholinoanilino)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C24H23ClN4O3

Similarity:  0.6134453781512605

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[4-[4-(morpholine-4-carbonyl)anilino]-1,3,5-triazin-2-yl]amino]phenyl]prop-2-enamide

Formula:  C23H23N7O3

Similarity:  0.6115702479338843

Relative Targets:   Tyrosine-protein kinase BTK  |