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Approved Drugs

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Inhibitors

Name:  N-[3-[[2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C31H35F3N8O4

Similarity:  0.8613138686131386

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C30H36N8O4

Similarity:  0.835820895522388

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C31H39N9O3

Similarity:  0.7103448275862069

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C25H27N7O4

Similarity:  0.6764705882352942

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C30H36ClN7O3

Similarity:  0.6575342465753424

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C25H28ClN7O2

Similarity:  0.6470588235294118

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[4-(dimethylamino)-1-piperidyl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C28H34N8O3

Similarity:  0.6206896551724138

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H24ClN5O4

Similarity:  0.6204379562043796

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H30N8O3

Similarity:  0.6197183098591549

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[4-(diethylamino)-1-piperidyl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C30H38N8O3

Similarity:  0.5960264900662252

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[4-(2-fluoroethyl)piperazin-1-yl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C27H31FN8O3

Similarity:  0.5945945945945946

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H26ClN5O4

Similarity:  0.5886524822695035

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(morpholine-4-carbonyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H27N7O5

Similarity:  0.5850340136054422

Relative Targets:   Epidermal growth factor receptor  |

Name:  Rociletinib

Formula:  C27H28F3N7O3

Similarity:  0.5733333333333334

Relative Targets:   Epidermal growth factor receptor  |

Name:  WZ4002

Formula:  C25H27ClN6O3

Similarity:  0.5664335664335665

Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C25H27ClN6O2S

Similarity:  0.5664335664335665

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-(2-methoxy-4-morpholino-anilino)-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H29N7O4

Similarity:  0.5637583892617449

Relative Targets:   Epidermal growth factor receptor  |

Name:  N1'-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-N1-[3-(prop-2-enoylamino)phenyl]cyclopropane-1,1-dicarboxamide

Formula:  C30H34N8O4

Similarity:  0.5576923076923077

Relative Targets:   Epidermal growth factor receptor  |