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Approved Drugs
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Inhibitors
Name:  N-[3-[[2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C31H35F3N8O4
Similarity:  0.8613138686131386
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C30H36N8O4
Similarity:  0.835820895522388
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C31H39N9O3
Similarity:  0.7103448275862069
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C25H27N7O4
Similarity:  0.6764705882352942
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C30H36ClN7O3
Similarity:  0.6575342465753424
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C25H28ClN7O2
Similarity:  0.6470588235294118
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-[4-(dimethylamino)-1-piperidyl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C28H34N8O3
Similarity:  0.6206896551724138
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H24ClN5O4
Similarity:  0.6204379562043796
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C26H30N8O3
Similarity:  0.6197183098591549
Relative Targets:   Epidermal growth factor receptor  |
Name:  Jak3-IN-1
Formula:  C26H30ClN7O2
Similarity:  0.5985915492957746
Relative Targets:   Serine/threonine-protein kinase Sgk1  | Epidermal growth factor receptor  | Platelet-derived growth factor receptor beta  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Tyrosine-protein kinase JAK3  | Focal adhesion kinase 1  | Tyrosine-protein kinase BTK  | Tyrosine-protein kinase ITK/TSK  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[3-[[2-[4-[4-(diethylamino)-1-piperidyl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C30H38N8O3
Similarity:  0.5960264900662252
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-[4-(2-fluoroethyl)piperazin-1-yl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C27H31FN8O3
Similarity:  0.5945945945945946
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H26ClN5O4
Similarity:  0.5886524822695035
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(morpholine-4-carbonyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C26H27N7O5
Similarity:  0.5850340136054422
Relative Targets:   Epidermal growth factor receptor  |
Name:  Rociletinib
Formula:  C27H28F3N7O3
Similarity:  0.5733333333333334
Relative Targets:   Epidermal growth factor receptor  |
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.5664335664335665
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C25H27ClN6O2S
Similarity:  0.5664335664335665
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-(2-methoxy-4-morpholino-anilino)-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C27H29N7O4
Similarity:  0.5637583892617449
Relative Targets:   Epidermal growth factor receptor  |
Name:  N1'-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-N1-[3-(prop-2-enoylamino)phenyl]cyclopropane-1,1-dicarboxamide
Formula:  C30H34N8O4
Similarity:  0.5576923076923077
Relative Targets:   Epidermal growth factor receptor  |