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Approved Drugs

Name:  Osimertinib

Formula:  C28H33N7O2

Similarity:  0.5182481751824818

Inhibitors

Name:  N-[3-[[2-[4-(diethylamino)-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C25H29N7O3

Similarity:  0.7964601769911505

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(2,4-dimethoxyanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C22H22N6O4

Similarity:  0.7410714285714286

Relative Targets:   Epidermal growth factor receptor  |

Name:  N,N-diethyl-3-methoxy-4-[[4-[[3-(prop-2-enoylamino)phenyl]carbamoylamino]pyrimidin-2-yl]amino]benzamide

Formula:  C26H29N7O4

Similarity:  0.71900826446281

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(2-methoxyanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C21H20N6O3

Similarity:  0.6964285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[4-(dimethylamino)-1-piperidyl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C28H34N8O3

Similarity:  0.6796875

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(dimethylamino)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C22H23N7O2

Similarity:  0.6551724137931034

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C27H31N7O3

Similarity:  0.6535433070866141

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H30N8O3

Similarity:  0.6535433070866141

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C25H27N7O4

Similarity:  0.6507936507936508

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[4-(diethylamino)-1-piperidyl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C30H38N8O3

Similarity:  0.6492537313432836

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[4-(2-fluoroethyl)piperazin-1-yl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C27H31FN8O3

Similarity:  0.6363636363636364

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C29H33N7O3

Similarity:  0.6335877862595419

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C27H30N8O4

Similarity:  0.6287878787878788

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-[2-(Dimethylamino)ethyl-methylamino]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H33N7O3

Similarity:  0.6259541984732825

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(morpholine-4-carbonyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H27N7O5

Similarity:  0.6259541984732825

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(2-methoxyethoxy)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C23H24N6O4

Similarity:  0.592

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-5-isopropyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C30H36N8O4

Similarity:  0.5827338129496403

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C31H39N9O3

Similarity:  0.5724137931034483

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C30H36N8O4

Similarity:  0.5694444444444444

Relative Targets:   Epidermal growth factor receptor  |