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Approved Drugs
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 0.6944444444444444
Inhibitors
Name: 1-[(3R)-3-[4-amino-3-(4-fluoro-1-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H21FN6O
Similarity: 0.7959183673469388
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(2-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H22N6O
Similarity: 0.7938144329896907
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-[4-(dimethylamino)-1-naphthyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C25H27N7O
Similarity: 0.7572815533980582
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(1-methylindol-3-yl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C22H23N7O
Similarity: 0.7474747474747475
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-(4-amino-3-phenyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O
Similarity: 0.7419354838709677
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: (E)-2-[(2R)-2-[[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]pyrrolidine-1-carbonyl]-3-cyclopropyl-prop-2-enenitrile
Formula: C27H25N7O
Similarity: 0.7407407407407407
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[(3S)-3-[4-amino-3-(2-methyl-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H26N6O2
Similarity: 0.7129629629629629
Relative Targets: Tyrosine-protein kinase BTK |
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 0.6944444444444444
Relative Targets: Epidermal growth factor receptor | Tyrosine-protein kinase Lyn | Cytoplasmic tyrosine-protein kinase BMX | Tyrosine-protein kinase JAK3 | Tyrosine-protein kinase BTK | Potassium voltage-gated channel subfamily H member 2 | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3S)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C25H24N6O2
Similarity: 0.6944444444444444
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[(3R)-3-[4-amino-3-(4-benzyloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H26N6O2
Similarity: 0.6756756756756757
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H19FN6O
Similarity: 0.673469387755102
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O2
Similarity: 0.673469387755102
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(3-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H19FN6O
Similarity: 0.673469387755102
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-(4-amino-3-benzyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C20H22N6O
Similarity: 0.6666666666666666
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(4-benzyloxy-3-chloro-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H25ClN6O2
Similarity: 0.6637168141592921
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(3-quinolyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C21H19N7O
Similarity: 0.6601941747572816
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3S)-3-[4-amino-3-(3-quinolyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C21H19N7O
Similarity: 0.6601941747572816
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3S)-3-[4-amino-3-(2,6-dimethyl-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C27H28N6O2
Similarity: 0.6403508771929824
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[(3R)-3-[4-amino-3-[2-chloro-4-[(3-fluorophenyl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H24ClFN6O2
Similarity: 0.6379310344827587
Relative Targets: Epidermal growth factor receptor |