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Inhibitors

Name:  N-[3-[2-[2-methoxy-4-(3,4,5-trimethylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.8387096774193549

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H31N7O3

Similarity:  0.8360655737704918

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[4-(3,4-dimethylpiperazin-1-yl)-2-methoxy-anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-(trifluoromethyl)phenyl]prop-2-enamide

Formula:  C31H32F3N7O3

Similarity:  0.7938931297709924

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-methyl-phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.7121212121212122

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-2-methyl-phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.7121212121212122

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.706766917293233

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-fluoro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H30FN7O3

Similarity:  0.6992481203007519

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-bromo-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H30BrN7O3

Similarity:  0.6992481203007519

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-chloro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.6992481203007519

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-ethyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.6962962962962963

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-isopropyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C32H37N7O3

Similarity:  0.6861313868613139

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.6818181818181818

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6818181818181818

Relative Targets:   Epidermal growth factor receptor  |

Name:  Egfr-IN-1

Formula:  C28H30N6O4

Similarity:  0.6793893129770993

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[3-tert-butyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C33H39N7O3

Similarity:  0.6762589928057554

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-[2-(Dimethylamino)ethyl-methylamino]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H33N7O3

Similarity:  0.6691729323308271

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(3,4,5-trimethylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-(trifluoromethyl)phenyl]prop-2-enamide

Formula:  C32H34F3N7O3

Similarity:  0.6690140845070423

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-(trifluoromethyl)phenyl]prop-2-enamide

Formula:  C30H30F3N7O3

Similarity:  0.6642857142857143

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C28H30N8O4

Similarity:  0.6496350364963503

Relative Targets:   Epidermal growth factor receptor  |