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Approved Drugs
Inhibitors
Name:  1-[(3S)-3-[4-amino-3-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C26H24ClFN6O2
Similarity:  0.8362068965517241
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-(4-benzyloxy-3-chloro-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C26H25ClN6O2
Similarity:  0.788135593220339
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[3-chloro-4-[(3,4-difluorophenyl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C26H23ClF2N6O2
Similarity:  0.7622950819672131
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[3-chloro-4-[(4-fluorophenyl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C26H24ClFN6O2
Similarity:  0.7603305785123967
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[3-chloro-4-(2-pyridylmethoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C25H24ClN7O2
Similarity:  0.7295081967213115
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[3-chloro-4-[(1-methylindazol-3-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C28H27ClN8O2
Similarity:  0.7076923076923077
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[3-chloro-4-[(1-methylimidazol-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C24H25ClN8O2
Similarity:  0.6935483870967742
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[2-chloro-4-[(3-fluorophenyl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C26H24ClFN6O2
Similarity:  0.6904761904761905
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[2,5-dichloro-4-[(3-fluorophenyl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C26H23Cl2FN6O2
Similarity:  0.6796875
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[3-methyl-4-[(6-methyl-2-pyridyl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C27H29N7O2
Similarity:  0.6771653543307087
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[3-methyl-4-(2-pyridylmethoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C26H27N7O2
Similarity:  0.6614173228346457
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[3-fluoro-4-(2-pyridylmethoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C25H24FN7O2
Similarity:  0.6484375
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-[3-methoxy-4-(2-pyridylmethoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C26H27N7O3
Similarity:  0.6461538461538462
Relative Targets:   Epidermal growth factor receptor  |
Name:  5-[4-amino-1-[(3R)-1-prop-2-enoyl-3-piperidyl]pyrazolo[3,4-d]pyrimidin-3-yl]-2-(2-pyridylmethoxy)benzonitrile
Formula:  C26H24N8O2
Similarity:  0.6335877862595419
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-(4-benzyloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C26H26N6O2
Similarity:  0.6328125
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-(2-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C23H22N6O
Similarity:  0.628099173553719
Relative Targets:   Epidermal growth factor receptor  | Mitogen-activated protein kinase kinase 7  |
Name:  N-[4-[4-amino-3-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]cyclohexyl]prop-2-enamide
Formula:  C27H26ClFN6O2
Similarity:  0.6240601503759399
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-1-[(3R)-3-[4-amino-3-[3-chloro-4-(2-pyridylmethoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-4-(dimethylamino)but-2-en-1-one
Formula:  C28H31ClN8O2
Similarity:  0.6204379562043796
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[(3R)-3-[4-amino-3-(3-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C19H19FN6O
Similarity:  0.5982905982905983
Relative Targets:   Epidermal growth factor receptor  |