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Inhibitors

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H31N7O3

Similarity:  0.75

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H26N8O2

Similarity:  0.7073170731707317

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[3-[5-methyl-2-[[1-(1-methyl-4-piperidyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C26H28N8O2

Similarity:  0.6991869918699187

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6796875

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.6417910447761194

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.6412213740458015

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-isopropyl-2-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C30H34N8O3

Similarity:  0.6370370370370371

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(3,4-dimethylpiperazin-1-yl)-2-methoxy-anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.6343283582089553

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-methyl-2-[(5-methyl-6,7-dihydro-4H-thiazolo[5,4-c]pyridin-2-yl)amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C24H23N7O2S

Similarity:  0.624

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-methyl-phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.6222222222222222

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-2-methyl-phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.6222222222222222

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-fluoro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H30FN7O3

Similarity:  0.6222222222222222

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-bromo-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H30BrN7O3

Similarity:  0.6222222222222222

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-chloro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.6222222222222222

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-ethyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.6086956521739131

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C24H26N8O2

Similarity:  0.6031746031746031

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H26N8O2

Similarity:  0.6030534351145038

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-isopropyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C32H37N7O3

Similarity:  0.6

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-isopropyl-2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C30H34N8O4

Similarity:  0.6

Relative Targets:   Epidermal growth factor receptor  |