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Approved Drugs

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Inhibitors

Name:  N-[3-[5-methyl-2-[[1-(1-methyl-4-piperidyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C26H28N8O2

Similarity:  0.6722689075630253

Relative Targets:   Epidermal growth factor receptor  |

Name:  Egfr-IN-1

Formula:  C28H30N6O4

Similarity:  0.6504065040650406

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[3-[2-[4-[2-(Dimethylamino)ethyl-methylamino]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H33N7O3

Similarity:  0.64

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-methyl-2-[[6-(4-methylpiperazin-1-yl)-3-pyridyl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O2

Similarity:  0.6031746031746031

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C20H23N7O

Similarity:  0.5855855855855856

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[5-methyl-2-[(5-methyl-6,7-dihydro-4H-thiazolo[5,4-c]pyridin-2-yl)amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C24H23N7O2S

Similarity:  0.5819672131147541

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C22H24N8O2

Similarity:  0.5798319327731093

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C22H21N7O3

Similarity:  0.5666666666666667

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C23H23N7O3

Similarity:  0.5655737704918032

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H31N7O3

Similarity:  0.5447761194029851

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[4-(diethylamino)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H25N7O2

Similarity:  0.544

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(3,4-dimethylpiperazin-1-yl)-2-methoxy-anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.5367647058823529

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-(cyclopropylmethyl)-2-[[6-(dimethylamino)-3-pyridyl]amino]-8-oxo-purin-9-yl]phenyl]prop-2-enamide

Formula:  C25H26N8O2

Similarity:  0.5354330708661418

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[7-(2-methoxyethyl)-2-[(6-methoxy-3-pyridyl)amino]-8-oxo-purin-9-yl]phenyl]prop-2-enamide

Formula:  C23H23N7O4

Similarity:  0.5317460317460317

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[2-(4-chloroanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C21H15ClN6O2

Similarity:  0.5294117647058824

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[(1-methylpyrazol-4-yl)amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C21H19N7O2

Similarity:  0.5294117647058824

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[2-methoxy-4-(3,4,5-trimethylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.5289855072463768

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-methoxyanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C22H18N6O3

Similarity:  0.5289256198347108

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[3-(2-anilino-7-oxo-pteridin-8-yl)phenyl]prop-2-enamide

Formula:  C21H16N6O2

Similarity:  0.5254237288135594

Relative Targets:   Epidermal growth factor receptor  |