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Inhibitors

Name:  N-[3-fluoro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H30FN7O3

Similarity:  0.8991596638655462

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-bromo-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H30BrN7O3

Similarity:  0.8991596638655462

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-chloro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.8991596638655462

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-ethyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.8925619834710744

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-isopropyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C32H37N7O3

Similarity:  0.8780487804878049

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-tert-butyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C33H39N7O3

Similarity:  0.864

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-(trifluoromethyl)phenyl]prop-2-enamide

Formula:  C30H30F3N7O3

Similarity:  0.8492063492063492

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H31N7O3

Similarity:  0.8360655737704918

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |

Name:  N-[5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-2-methyl-phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.8225806451612904

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.732824427480916

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[4-(3,4-dimethylpiperazin-1-yl)-2-methoxy-anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-(trifluoromethyl)phenyl]prop-2-enamide

Formula:  C31H32F3N7O3

Similarity:  0.7279411764705882

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(3,4-dimethylpiperazin-1-yl)-2-methoxy-anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.7121212121212122

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.6818181818181818

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6818181818181818

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(3,4,5-trimethylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-(trifluoromethyl)phenyl]prop-2-enamide

Formula:  C32H34F3N7O3

Similarity:  0.6690140845070423

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C28H30N8O4

Similarity:  0.6617647058823529

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-5H-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O4

Similarity:  0.6592592592592592

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6567164179104478

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[5-ethyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.6546762589928058

Relative Targets:   Tyrosine-protein kinase JAK3  |