Searching results
Approved Drugs
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 0.5964912280701754
Inhibitors
Name: 1-[(3R)-3-(4-amino-3-phenyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O
Similarity: 0.7692307692307693
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: (E)-1-[(3R)-3-[4-amino-3-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-4-(dimethylamino)but-2-en-1-one
Formula: C23H26F3N7O
Similarity: 0.7572815533980582
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: (E)-1-[(3R)-3-[4-amino-3-[3-chloro-4-(2-pyridylmethoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-4-(dimethylamino)but-2-en-1-one
Formula: C28H31ClN8O2
Similarity: 0.6779661016949152
Relative Targets: Epidermal growth factor receptor |
Name: (E)-1-[3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]but-2-en-1-one
Formula: C26H26N6O2
Similarity: 0.6371681415929203
Relative Targets: Tyrosine-protein kinase BTK |
Name: (E)-3-[4-amino-7-(3-hydroxypropyl)-5-(p-tolyl)pyrrolo[2,3-d]pyrimidin-6-yl]-2-cyano-N-isopropyl-prop-2-enamide
Formula: C23H23N7O
Similarity: 0.6355140186915887
Relative Targets: Ribosomal protein S6 kinase alpha-3 |
Name: 1-[(3R)-3-(4-amino-3-benzyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C20H22N6O
Similarity: 0.6237623762376238
Relative Targets: Epidermal growth factor receptor |
Name: (E)-1-[3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-chloro-prop-2-en-1-one
Formula: C25H23ClN6O2
Similarity: 0.6228070175438597
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[(3R)-3-[4-amino-3-(3-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H19FN6O
Similarity: 0.6138613861386139
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-[4-(dimethylamino)-1-naphthyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C25H27N7O
Similarity: 0.6071428571428571
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(2-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H22N6O
Similarity: 0.6018518518518519
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H19FN6O
Similarity: 0.5980392156862745
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O2
Similarity: 0.5980392156862745
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 0.5964912280701754
Relative Targets: Epidermal growth factor receptor | Tyrosine-protein kinase Lyn | Cytoplasmic tyrosine-protein kinase BMX | Tyrosine-protein kinase JAK3 | Tyrosine-protein kinase BTK | Potassium voltage-gated channel subfamily H member 2 | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3S)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C25H24N6O2
Similarity: 0.5964912280701754
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[(3R)-3-[4-amino-3-(4-benzyloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H26N6O2
Similarity: 0.5948275862068966
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(1-methylindol-3-yl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C22H23N7O
Similarity: 0.5925925925925926
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H22N6O
Similarity: 0.5871559633027523
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C20H19F3N6O
Similarity: 0.5740740740740741
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-benzyloxy-3-chloro-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H25ClN6O2
Similarity: 0.5714285714285714
Relative Targets: Epidermal growth factor receptor |