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Approved Drugs
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Inhibitors
Name: 2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pyrido[2,3-d]pyrimidin-7-one
Formula: C27H33N7O3
Similarity: 1.0
Relative Targets: Epidermal growth factor receptor |
Name: 2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-(1-prop-2-enoyl-4-piperidyl)pyrido[2,3-d]pyrimidin-7-one
Formula: C28H35N7O3
Similarity: 0.9017857142857143
Relative Targets: Epidermal growth factor receptor |
Name: 2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-[(1-prop-2-enoylpyrrolidin-3-yl)methyl]pyrido[2,3-d]pyrimidin-7-one
Formula: C28H35N7O3
Similarity: 0.8362068965517241
Relative Targets: Epidermal growth factor receptor |
Name: 2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pteridin-7-one
Formula: C25H30N8O3
Similarity: 0.808695652173913
Relative Targets: Tyrosine-protein kinase BTK |
Name: 2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]pteridin-7-one
Formula: C25H30N8O3
Similarity: 0.808695652173913
Relative Targets: Tyrosine-protein kinase BTK |
Name: 2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3S)-1-prop-2-enoyl-3-piperidyl]pteridin-7-one
Formula: C26H32N8O3
Similarity: 0.7583333333333333
Relative Targets: Tyrosine-protein kinase BTK |
Name: 2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3R)-1-prop-2-enoyl-3-piperidyl]pteridin-7-one
Formula: C26H32N8O3
Similarity: 0.7583333333333333
Relative Targets: Tyrosine-protein kinase BTK |
Name: 2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-(1-prop-2-enoyl-4-piperidyl)pteridin-7-one
Formula: C26H32N8O3
Similarity: 0.7295081967213115
Relative Targets: Tyrosine-protein kinase BTK |
Name: 7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C26H34N8O3
Similarity: 0.7073170731707317
Relative Targets: Epidermal growth factor receptor |
Name: 3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C28H38N8O3
Similarity: 0.6796875
Relative Targets: Epidermal growth factor receptor |
Name: 7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C31H36N8O3
Similarity: 0.6376811594202898
Relative Targets: Epidermal growth factor receptor |
Name: 3-cyclopentyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C30H40N8O3
Similarity: 0.6277372262773723
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O3
Similarity: 0.624113475177305
Relative Targets: Epidermal growth factor receptor |
Name: 3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one
Formula: C32H38N8O3
Similarity: 0.624113475177305
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula: C29H31N7O3
Similarity: 0.6240601503759399
Relative Targets: Epidermal growth factor receptor | Tyrosine-protein kinase JAK3 |
Name: N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-methyl-phenyl]prop-2-enamide
Formula: C30H33N7O3
Similarity: 0.6148148148148148
Relative Targets: Epidermal growth factor receptor |
Name: N-[5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-2-methyl-phenyl]prop-2-enamide
Formula: C30H33N7O3
Similarity: 0.6148148148148148
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-fluoro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula: C29H30FN7O3
Similarity: 0.6148148148148148
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-bromo-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula: C29H30BrN7O3
Similarity: 0.6148148148148148
Relative Targets: Epidermal growth factor receptor |