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Approved Drugs
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 0.696078431372549
Inhibitors
Name: 1-[(3R)-3-[4-amino-3-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H19FN6O
Similarity: 0.8554216867469879
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-[4-(trifluoromethyl)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C20H19F3N6O
Similarity: 0.7888888888888889
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-(4-amino-3-phenyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O
Similarity: 0.7674418604651163
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(3-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H19FN6O
Similarity: 0.75
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(2-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H22N6O
Similarity: 0.7263157894736842
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 0.696078431372549
Relative Targets: Epidermal growth factor receptor | Tyrosine-protein kinase Lyn | Cytoplasmic tyrosine-protein kinase BMX | Tyrosine-protein kinase JAK3 | Tyrosine-protein kinase BTK | Potassium voltage-gated channel subfamily H member 2 | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3S)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C25H24N6O2
Similarity: 0.696078431372549
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-[(3R)-3-[4-amino-3-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C20H19F3N6O
Similarity: 0.6947368421052632
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C20H20N8O
Similarity: 0.6770833333333334
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-benzyloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H26N6O2
Similarity: 0.6761904761904762
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H22N6O
Similarity: 0.673469387755102
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-fluoro-1-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H21FN6O
Similarity: 0.66
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(1-methylindol-3-yl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C22H23N7O
Similarity: 0.6464646464646465
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-[1-(4-bromophenyl)triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C21H20BrN9O
Similarity: 0.6407766990291263
Relative Targets: Dual specificity mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-(4-amino-3-iodo-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C13H15IN6O
Similarity: 0.6385542168674698
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C24H22N6O2
Similarity: 0.6346153846153846
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(4-benzyloxy-3-chloro-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C26H25ClN6O2
Similarity: 0.6330275229357798
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-(4-amino-3-benzyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C20H22N6O
Similarity: 0.631578947368421
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-[4-(dimethylamino)-1-naphthyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C25H27N7O
Similarity: 0.6285714285714286
Relative Targets: Epidermal growth factor receptor |