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Approved Drugs
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.5267175572519084
Name: Neratinib
Formula: C30H29ClN6O3
Similarity: 0.5174825174825175
Inhibitors
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C28H26ClFN6O2
Similarity: 0.768595041322314
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C30H31ClFN5O4
Similarity: 0.7322834645669292
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C31H33ClFN5O4
Similarity: 0.7153846153846154
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C31H31ClFN5O4
Similarity: 0.7099236641221374
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C19H18ClFN6O
Similarity: 0.7009345794392523
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (Z)-N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H26ClF2N5O3
Similarity: 0.6640625
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H26ClF2N5O3
Similarity: 0.6640625
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide
Formula: C30H32FN5O4
Similarity: 0.6268656716417911
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C27H26N8O
Similarity: 0.625
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C31H29ClFN5O3
Similarity: 0.6222222222222222
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-4-(dimethylamino)-N-[4-[4-(2-pyridylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C25H25N7O
Similarity: 0.6178861788617886
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C29H31ClN6O4
Similarity: 0.6148148148148148
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula: C31H32FN5O4
Similarity: 0.6086956521739131
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C31H31ClFN5O3
Similarity: 0.6086956521739131
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula: C27H24ClFN4O4
Similarity: 0.6076923076923076
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C25H24N6O2
Similarity: 0.6048387096774194
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxy-quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula: C32H34ClFN6O3
Similarity: 0.5985915492957746
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C30H31ClN6O4
Similarity: 0.5971223021582733
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C23H25ClFN5O3
Similarity: 0.568
Relative Targets: Epidermal growth factor receptor |