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Approved Drugs

Name:  Dacomitinib

Formula:  C24H25ClFN5O2

Similarity:  0.56

Name:  Afatinib

Formula:  C24H25ClFN5O3

Similarity:  0.5271317829457365

Inhibitors

Name:  Canertinib

Formula:  C24H25ClFN5O3

Similarity:  0.8504672897196262

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride

Formula:  C24H27Cl3FN5O3

Similarity:  0.8348623853211009

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]but-2-enamide

Formula:  C25H27ClFN5O3

Similarity:  0.8272727272727273

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]cyclopentene-1-carboxamide

Formula:  C27H29ClFN5O3

Similarity:  0.7627118644067796

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromo-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C24H25BrFN5O3

Similarity:  0.7522123893805309

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C23H22ClF2N5O3

Similarity:  0.7130434782608696

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C23H22ClF2N5O3

Similarity:  0.7130434782608696

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C23H24ClFN6O3

Similarity:  0.6923076923076923

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-methylanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C25H29N5O3

Similarity:  0.6896551724137931

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromoanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C24H26BrN5O3

Similarity:  0.6752136752136753

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]-N-methyl-prop-2-enamide

Formula:  C24H26ClFN6O3

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C26H26ClF2N5O4

Similarity:  0.627906976744186

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C26H26ClF2N5O4

Similarity:  0.627906976744186

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N'-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-morpholinopropyl)but-2-enediamide

Formula:  C24H25ClFN7O3

Similarity:  0.59375

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C26H29ClFN5O3

Similarity:  0.59375

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C24H24ClF2N5O2

Similarity:  0.5887096774193549

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C24H24ClF2N5O2

Similarity:  0.5887096774193549

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C25H27ClFN5O4S

Similarity:  0.5846153846153846

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(4-morpholinobutyl)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C24H26ClFN6O2

Similarity:  0.584

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |