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Approved Drugs
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Inhibitors
Name: (E)-N-[4-[4-(2-pyridylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C27H27N7O
Similarity: 0.7543859649122807
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-4-(4-methylpiperazin-1-yl)-N-[4-[4-(2-pyridylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C28H30N8O
Similarity: 0.7372881355932204
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-4-(dimethylamino)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C25H24N6O2
Similarity: 0.7142857142857143
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C27H26N8O
Similarity: 0.6611570247933884
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C19H18ClFN6O
Similarity: 0.6203703703703703
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C26H24ClFN6O2
Similarity: 0.6178861788617886
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-4-(dimethylamino)-N-[7-(2-methoxyethoxy)-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]but-2-enamide
Formula: C29H32N6O4
Similarity: 0.6076923076923076
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[7-methoxy-4-[4-(2-pyridylmethyl)anilino]quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C29H30N6O2
Similarity: 0.6015625
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-4-(dimethylamino)-N-[4-[4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula: C30H32N6O4
Similarity: 0.5895522388059702
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C20H20BrN5O
Similarity: 0.5446428571428571
Relative Targets: Proto-oncogene tyrosine-protein kinase Src | Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-4-(dimethylamino)-N-[4-(3-iodoanilino)quinazolin-6-yl]but-2-enamide
Formula: C20H20IN5O
Similarity: 0.5446428571428571
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C29H31ClN6O4
Similarity: 0.5401459854014599
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C27H26N6O2
Similarity: 0.5384615384615384
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-3-phenyl-prop-2-enamide
Formula: C22H16BrN5O
Similarity: 0.5338983050847458
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C30H31ClN6O4
Similarity: 0.524822695035461
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C30H31N7O2
Similarity: 0.5144927536231884
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C29H28N8O
Similarity: 0.5035971223021583
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C17H14BrN5O
Similarity: 0.5
Relative Targets: Epidermal growth factor receptor |