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Approved Drugs
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Inhibitors
Name: (E)-4-(4-methylpiperazin-1-yl)-N-[4-[4-(2-pyridylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C28H30N8O
Similarity: 0.8521739130434782
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[7-methoxy-4-[4-(2-pyridylmethyl)anilino]quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C29H30N6O2
Similarity: 0.7899159663865546
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-4-(dimethylamino)-N-[4-[4-(2-pyridylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C25H25N7O
Similarity: 0.7543859649122807
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C27H26N6O2
Similarity: 0.7333333333333333
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C29H28N8O
Similarity: 0.6821705426356589
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[7-ethoxy-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C30H32N6O3
Similarity: 0.6590909090909091
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C28H26ClFN6O2
Similarity: 0.6412213740458015
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C22H22ClFN6O
Similarity: 0.6302521008403361
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[7-ethoxy-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula: C31H35N7O3
Similarity: 0.5664335664335665
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[7-methoxy-4-(4-phenoxyanilino)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C30H31N5O3
Similarity: 0.5652173913043478
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C23H24BrN5O
Similarity: 0.5609756097560976
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-morpholino-but-2-enamide
Formula: C21H20ClFN6O2
Similarity: 0.552
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[4-(benzenesulfonamido)anilino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C30H32N6O4S
Similarity: 0.5486111111111112
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula: C22H23ClFN7O
Similarity: 0.5433070866141733
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C32H33N7O2
Similarity: 0.541095890410959
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-4-(dimethylamino)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C25H24N6O2
Similarity: 0.5384615384615384
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C33H35N7O2
Similarity: 0.5302013422818792
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C33H35N7O3
Similarity: 0.5197368421052632
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C27H26N8O
Similarity: 0.5144927536231884
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |