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Approved Drugs

Name:  Dacomitinib

Formula:  C24H25ClFN5O2

Similarity:  0.6228070175438597

Name:  Afatinib

Formula:  C24H25ClFN5O3

Similarity:  0.5327868852459017

Inhibitors

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C22H22ClFN6O

Similarity:  0.8181818181818182

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide

Formula:  C22H23ClFN7O

Similarity:  0.801980198019802

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N'-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-morpholinopropyl)but-2-enediamide

Formula:  C24H25ClFN7O3

Similarity:  0.7636363636363637

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C19H18ClFN6O

Similarity:  0.69

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C16H11ClFN5O

Similarity:  0.6631578947368421

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-morpholino-but-2-enamide

Formula:  C22H22BrN5O2

Similarity:  0.6330275229357798

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]but-2-enamide

Formula:  C25H27ClFN5O3

Similarity:  0.6324786324786325

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C23H22ClF2N5O3

Similarity:  0.6260869565217392

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C23H22ClF2N5O3

Similarity:  0.6260869565217392

Relative Targets:   Epidermal growth factor receptor  |

Name:  Dacomitinib

Formula:  C24H25ClFN5O2

Similarity:  0.6228070175438597

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-6-quinolyl]-4-morpholino-but-2-enamide

Formula:  C24H21ClFN5O2

Similarity:  0.6228070175438597

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide

Formula:  C28H26ClFN6O2

Similarity:  0.6209677419354839

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C23H23ClFN5O3S

Similarity:  0.6120689655172413

Relative Targets:   Epidermal growth factor receptor  |

Name:  Canertinib

Formula:  C24H25ClFN5O3

Similarity:  0.6068376068376068

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N'-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-morpholinopropyl)but-2-enediamide

Formula:  C24H26BrN7O3

Similarity:  0.6

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C27H29ClFN5O3

Similarity:  0.5967741935483871

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-morpholino-but-2-enamide

Formula:  C25H23ClFN5O3

Similarity:  0.5966386554621849

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride

Formula:  C24H27Cl3FN5O3

Similarity:  0.5966386554621849

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(E)-4-morpholinobut-1-enyl]pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C24H24ClFN6O2

Similarity:  0.5932203389830508

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |