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Approved Drugs
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Inhibitors
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C32H33N7O2
Similarity: 0.7862595419847328
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C27H26N8O
Similarity: 0.7723577235772358
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C33H35N7O2
Similarity: 0.7686567164179104
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C33H35N7O3
Similarity: 0.7518248175182481
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C27H26N6O2
Similarity: 0.6953125
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-morpholino-but-2-enamide
Formula: C32H33N7O3
Similarity: 0.6928571428571428
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula: C33H36N8O2
Similarity: 0.6830985915492958
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[4-(2-pyridylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C27H27N7O
Similarity: 0.6821705426356589
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula: C34H38N8O3
Similarity: 0.6554054054054054
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C28H26ClFN6O2
Similarity: 0.6470588235294118
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-[(2S,6R)-2,6-dimethyl-1-piperidyl]but-2-enamide
Formula: C35H39N7O2
Similarity: 0.6174496644295302
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]but-2-enamide
Formula: C34H38N8O2
Similarity: 0.6174496644295302
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C22H22ClFN6O
Similarity: 0.6111111111111112
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C30H31N7O2
Similarity: 0.6028368794326241
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-4-(4-methylpiperazin-1-yl)-N-[4-[4-(2-pyridylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Formula: C28H30N8O
Similarity: 0.5971223021582733
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-[(2R,6S)-2,6-dimethylpiperazin-1-yl]but-2-enamide
Formula: C34H38N8O2
Similarity: 0.5960264900662252
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C32H32N6O4S
Similarity: 0.5866666666666667
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C31H33N7O3
Similarity: 0.5782312925170068
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[7-methoxy-4-[4-(2-pyridylmethyl)anilino]quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C29H30N6O2
Similarity: 0.574468085106383
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |