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Approved Drugs

Name:  Dacomitinib

Formula:  C24H25ClFN5O2

Similarity:  0.5378787878787878

Inhibitors

Name:  Canertinib

Formula:  C24H25ClFN5O3

Similarity:  0.7758620689655172

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride

Formula:  C24H27Cl3FN5O3

Similarity:  0.7627118644067796

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]-2-methyl-prop-2-enamide

Formula:  C25H27ClFN5O3

Similarity:  0.7627118644067796

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]but-2-enamide

Formula:  C25H27ClFN5O3

Similarity:  0.7563025210084033

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromo-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C24H25BrFN5O3

Similarity:  0.6885245901639344

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C23H24ClFN6O3

Similarity:  0.6349206349206349

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-methylanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C25H29N5O3

Similarity:  0.632

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-bromoanilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C24H26BrN5O3

Similarity:  0.632

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C23H22ClF2N5O3

Similarity:  0.6141732283464567

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C23H22ClF2N5O3

Similarity:  0.6141732283464567

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)pyrido[3,2-d]pyrimidin-6-yl]-N-methyl-prop-2-enamide

Formula:  C24H26ClFN6O3

Similarity:  0.6

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C26H26ClF2N5O4

Similarity:  0.5912408759124088

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C26H26ClF2N5O4

Similarity:  0.5912408759124088

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C26H29ClFN5O3

Similarity:  0.5703703703703704

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N'-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-N-(3-morpholinopropyl)but-2-enediamide

Formula:  C24H25ClFN7O3

Similarity:  0.5474452554744526

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(4-oxo-1-piperidyl)but-2-enamide

Formula:  C27H27ClFN5O4

Similarity:  0.5460992907801419

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C27H29ClFN5O3

Similarity:  0.5428571428571428

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C25H27ClFN5O4S

Similarity:  0.539568345323741

Relative Targets:   Epidermal growth factor receptor  |

Name:  Dacomitinib

Formula:  C24H25ClFN5O2

Similarity:  0.5378787878787878

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |