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Approved Drugs
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.5524475524475524
Inhibitors
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C32H33N7O2
Similarity: 0.8931297709923665
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula: C34H38N8O3
Similarity: 0.8768115942028986
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C33H35N7O2
Similarity: 0.8731343283582089
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C31H33N7O3
Similarity: 0.7956204379562044
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-morpholino-but-2-enamide
Formula: C32H33N7O3
Similarity: 0.7928571428571428
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula: C33H36N8O2
Similarity: 0.7816901408450704
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C29H28N8O
Similarity: 0.7518248175182481
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-[(2S,6R)-2,6-dimethyl-1-piperidyl]but-2-enamide
Formula: C35H39N7O2
Similarity: 0.7114093959731543
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]but-2-enamide
Formula: C34H38N8O2
Similarity: 0.7114093959731543
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C30H31N7O2
Similarity: 0.7021276595744681
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-[(2R,6S)-2,6-dimethylpiperazin-1-yl]but-2-enamide
Formula: C34H38N8O2
Similarity: 0.6887417218543046
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C32H32N6O4S
Similarity: 0.6688741721854304
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(diisopropylamino)but-2-enamide
Formula: C34H39N7O2
Similarity: 0.6556291390728477
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C26H29ClFN5O3
Similarity: 0.65
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[7-methoxy-4-(4-phenoxyanilino)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C30H31N5O3
Similarity: 0.6258503401360545
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[7-methoxy-4-[4-(2-pyridylmethyl)anilino]quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C29H30N6O2
Similarity: 0.6164383561643836
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[7-ethoxy-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C30H32N6O3
Similarity: 0.6133333333333333
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C31H31ClFN5O3
Similarity: 0.6078431372549019
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[4-(benzenesulfonamido)anilino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C30H32N6O4S
Similarity: 0.6078431372549019
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |