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Name:  Dacomitinib

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.68

Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6037735849056604

Name:  N-[4-(3-Chloro-4-fluoroanilino)-7-prop-2-ynoxyquinazolin-6-yl]prop-2-enamide

Formula:  C₂₀H₁₄ClFN₄O₂

Similarity:  0.8095238095238095

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈ClFN₄O₃

Similarity:  0.7472527472527473

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-pyrido[3,2-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₁₇H₁₃ClFN₅O₂

Similarity:  0.7380952380952381

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide

Formula:  C₂₂H₂₁ClFN₅O₂

Similarity:  0.7311827956989247

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C₂₃H₂₃ClFN₅O₂

Similarity:  0.7157894736842105

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₁H₂₀ClF₂N₅O₂

Similarity:  0.7096774193548387

Relative Targets:   Tyrosine-protein kinase JAK2  | Epidermal growth factor receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor alpha  | Fibroblast growth factor receptor 2  | RAC-beta serine/threonine-protein kinase  | Potassium voltage-gated channel subfamily H member 2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)quinazolin-6-yl]prop-2-enamide

Formula:  C₁₇H₁₂ClFN₄O

Similarity:  0.6987951807228916

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]prop-2-enamide

Formula:  C₁₆H₁₁ClFN₅O

Similarity:  0.6987951807228916

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[2-(4-hydroxybutoxy)ethoxy]quinazolin-6-yl]prop-2-enamide

Formula:  C₂₃H₂₄ClFN₄O₄

Similarity:  0.6868686868686869

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(diisopropylamino)but-2-enamide

Formula:  C₂₅H₂₉ClFN₅O₂

Similarity:  0.6868686868686869

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈FN₅O₃

Similarity:  0.6808510638297872

Relative Targets:   Epidermal growth factor receptor  |

Name:  Dacomitinib

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.68

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[(3,3-difluorocyclobutyl)amino]but-2-enamide

Formula:  C₂₃H₂₁ClF₃N₅O₂

Similarity:  0.68

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide

Formula:  C₂₅H₂₅ClFN₅O₂

Similarity:  0.6732673267326733

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C₂₃H₂₃ClFN₅O₃S

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  Canertinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6601941747572816

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈ClF₃N₄O₃

Similarity:  0.6530612244897959

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride

Formula:  C₂₄H₂₇Cl₃FN₅O₃

Similarity:  0.6476190476190476

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₃H₂₅ClFN₅O₃

Similarity:  0.6435643564356436

Relative Targets:   Epidermal growth factor receptor  |