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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5

Inhibitors

Name:  methyl-[2-(4-morpholinoanilino)-4-[3-(prop-2-enoylamino)anilino]pyrimidin-5-yl]-oxido-sulfonium

Formula:  C24H26N6O3S

Similarity:  0.8301886792452831

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.7297297297297297

Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6880733944954128

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-(4-morpholinoanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C24H25N7O3

Similarity:  0.6810344827586207

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.65

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(2-methoxyethoxy)anilino]-5-methylsulfanyl-pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C23H25N5O3S

Similarity:  0.6491228070175439

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6283185840707964

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6140350877192983

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[4-[4-(morpholine-4-carbonyl)anilino]-1,3,5-triazin-2-yl]amino]phenyl]prop-2-enamide

Formula:  C23H23N7O3

Similarity:  0.6134453781512605

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.6120689655172413

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[7-(cyclopropylmethyl)-2-(4-morpholinoanilino)-8-oxo-purin-9-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.609375

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  [2-[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl] prop-2-enoate

Formula:  C23H22ClN5O3

Similarity:  0.6016949152542372

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[3-[[3-chloro-6-(4-morpholinoanilino)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C24H23ClN4O3

Similarity:  0.6016949152542372

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C24H25ClN6OS

Similarity:  0.5916666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.584

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.5785123966942148

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25BrN6O2

Similarity:  0.5785123966942148

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C25H27N7O4

Similarity:  0.5748031496062992

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.5726495726495726

Relative Targets:   Tyrosine-protein kinase JAK3  |