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Approved Drugs
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Inhibitors
Name: Rociletinib
Formula: C27H28F3N7O3
Similarity: 0.8211382113821138
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-(trifluoromethyl)-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula: C27H28F3N5O3
Similarity: 0.7244094488188977
Relative Targets: Dipeptidyl peptidase 1 |
Name: WZ4002
Formula: C25H27ClN6O3
Similarity: 0.7235772357723578
Relative Targets: Epidermal growth factor receptor | Dipeptidyl peptidase 1 |
Name: N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula: C25H24ClF3N6O2
Similarity: 0.7142857142857143
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula: C25H25F3N6O2
Similarity: 0.6850393700787402
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-3-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula: C27H28F3N7O3
Similarity: 0.6842105263157895
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula: C26H27ClN6O4
Similarity: 0.6692307692307692
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula: C24H24ClN5O4
Similarity: 0.6535433070866141
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula: C30H31N7O4
Similarity: 0.6474820143884892
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula: C25H26ClN5O4
Similarity: 0.6434108527131783
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula: C26H28ClN5O3
Similarity: 0.6183206106870229
Relative Targets: Dipeptidyl peptidase 1 |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Formula: C28H31ClN6O3
Similarity: 0.6131386861313869
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula: C26H26ClF3N6O2
Similarity: 0.6102941176470589
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-5-fluoro-phenyl]prop-2-enamide
Formula: C25H26ClFN6O3
Similarity: 0.6090225563909775
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula: C30H36ClN7O3
Similarity: 0.6083916083916084
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula: C25H27ClN6O2S
Similarity: 0.6060606060606061
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula: C25H28ClN7O2
Similarity: 0.6060606060606061
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[3-cyano-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula: C27H28N6O3
Similarity: 0.6044776119402985
Relative Targets: Dipeptidyl peptidase 1 |
Name: N-[3-[[3-ethynyl-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula: C28H29N5O3
Similarity: 0.6044776119402985
Relative Targets: Dipeptidyl peptidase 1 |