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Approved Drugs
Inhibitors
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C26H27N5O3
Similarity:  0.8256880733944955
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C27H27N5O3
Similarity:  0.8125
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.7787610619469026
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C23H20N4O3
Similarity:  0.7735849056603774
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-tetrahydropyran-4-yloxy-quinazolin-6-yl]but-2-enamide
Formula:  C27H29N5O3
Similarity:  0.7413793103448276
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C29H31N5O3
Similarity:  0.7213114754098361
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula:  C24H23N5O2
Similarity:  0.6964285714285714
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula:  C25H25N5O2
Similarity:  0.6782608695652174
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-[(1-methyl-4-piperidyl)oxy]quinazolin-6-yl]but-2-enamide
Formula:  C28H32N6O2
Similarity:  0.6585365853658537
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-[cyclopropyl(methyl)amino]-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula:  C25H25N5O2
Similarity:  0.6551724137931034
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-[cyclopropyl(methyl)amino]-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula:  C26H27N5O2
Similarity:  0.6386554621848739
Relative Targets:   Epidermal growth factor receptor  |
Name:  Afatinib
Formula:  C24H25ClFN5O3
Similarity:  0.6363636363636364
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |
Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C25H25FN6O3
Similarity:  0.6341463414634146
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula:  C25H25ClFN5O3
Similarity:  0.6290322580645161
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H25ClFN5O3
Similarity:  0.6097560975609756
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C26H27N5O2
Similarity:  0.6016260162601627
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C25H25ClF3N5O3
Similarity:  0.6015625
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C27H29N5O2
Similarity:  0.5873015873015873
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide
Formula:  C25H27N5O3
Similarity:  0.5853658536585366
Relative Targets:   Epidermal growth factor receptor  |