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Approved Drugs
Inhibitors
Name:  (E)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C26H27N5O2
Similarity:  0.8932038834951457
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C29H31N5O3
Similarity:  0.7777777777777778
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula:  C25H25N5O2
Similarity:  0.7207207207207207
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-[cyclopropyl(methyl)amino]-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula:  C26H27N5O2
Similarity:  0.7079646017699115
Relative Targets:   Epidermal growth factor receptor  |
Name:  Dacomitinib
Formula:  C24H25ClFN5O2
Similarity:  0.6869565217391305
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C26H29ClFN5O3
Similarity:  0.6776859504132231
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C33H35N7O2
Similarity:  0.6518518518518519
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula:  C31H31ClFN5O3
Similarity:  0.6515151515151515
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula:  C24H23N5O2
Similarity:  0.6347826086956522
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[7-ethoxy-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula:  C30H32N6O3
Similarity:  0.6335877862595419
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula:  C32H33N7O2
Similarity:  0.6296296296296297
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-[(1-methyl-4-piperidyl)oxy]quinazolin-6-yl]but-2-enamide
Formula:  C28H32N6O2
Similarity:  0.6290322580645161
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C23H24BrN5O
Similarity:  0.6260869565217392
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-4-[cyclopropyl(methyl)amino]-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula:  C25H25N5O2
Similarity:  0.6239316239316239
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide
Formula:  C25H27N5O3
Similarity:  0.6218487394957983
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[4-(benzenesulfonamido)anilino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula:  C30H32N6O4S
Similarity:  0.6148148148148148
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula:  C32H32N6O4S
Similarity:  0.6115107913669064
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C22H20N4O3
Similarity:  0.6106194690265486
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C27H29ClFN5O3
Similarity:  0.6046511627906976
Relative Targets:   Epidermal growth factor receptor  |