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Approved Drugs
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.6666666666666666
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.6134453781512605
Inhibitors
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C22H21ClFN5O2
Similarity: 0.8484848484848485
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(difluoromethoxy)quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C22H19ClF3N5O2
Similarity: 0.7570093457943925
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C23H23ClFN5O2
Similarity: 0.7547169811320755
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2,2,2-trifluoroethoxy)quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C23H20ClF4N5O2
Similarity: 0.7232142857142857
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C23H23ClFN5O2
Similarity: 0.7129629629629629
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide
Formula: C18H14ClFN4O2
Similarity: 0.68
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula: C25H25ClFN5O2
Similarity: 0.6754385964912281
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C25H25ClFN5O3
Similarity: 0.6752136752136753
Relative Targets: Epidermal growth factor receptor |
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.6666666666666666
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide
Formula: C23H23ClFN5O3S
Similarity: 0.6551724137931034
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(diisopropylamino)but-2-enamide
Formula: C25H29ClFN5O2
Similarity: 0.6434782608695652
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula: C24H23N5O2
Similarity: 0.6428571428571429
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(3,3-difluoroazetidin-1-yl)but-2-enamide
Formula: C25H23ClF3N5O3
Similarity: 0.639344262295082
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide
Formula: C25H27ClFN5O3
Similarity: 0.6386554621848739
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C24H25ClFN5O2
Similarity: 0.6347826086956522
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C25H27ClFN5O3
Similarity: 0.6166666666666667
Relative Targets: Epidermal growth factor receptor |
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.6134453781512605
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Dipeptidyl peptidase 1 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C23H25ClFN5O3
Similarity: 0.6068376068376068
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula: C26H27ClFN5O2
Similarity: 0.6033057851239669
Relative Targets: Epidermal growth factor receptor |