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Approved Drugs
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.7102803738317757
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.6666666666666666
Inhibitors
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C23H23ClFN5O2
Similarity: 0.8842105263157894
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[(3,3-difluorocyclobutyl)amino]but-2-enamide
Formula: C23H21ClF3N5O2
Similarity: 0.8484848484848485
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(difluoromethoxy)quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C22H19ClF3N5O2
Similarity: 0.8469387755102041
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2,2,2-trifluoroethoxy)quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C23H20ClF4N5O2
Similarity: 0.8058252427184466
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C23H23ClFN5O2
Similarity: 0.797979797979798
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C25H25ClFN5O3
Similarity: 0.7830188679245284
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula: C24H23N5O2
Similarity: 0.7524752475247525
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula: C25H25ClFN5O2
Similarity: 0.7523809523809524
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide
Formula: C18H14ClFN4O2
Similarity: 0.7311827956989247
Relative Targets: Epidermal growth factor receptor |
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.7102803738317757
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C24H25ClFN5O2
Similarity: 0.7075471698113207
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide
Formula: C23H23ClFN5O3S
Similarity: 0.6972477064220184
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide
Formula: C25H27ClFN5O3
Similarity: 0.6936936936936937
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(diisopropylamino)but-2-enamide
Formula: C25H29ClFN5O2
Similarity: 0.6851851851851852
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula: C25H27ClFN5O3
Similarity: 0.6846846846846847
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula: C26H27ClFN5O2
Similarity: 0.6696428571428571
Relative Targets: Epidermal growth factor receptor |
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.6666666666666666
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Dipeptidyl peptidase 1 |
Name: (E)-4-(cyclopropylamino)-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula: C25H25N5O2
Similarity: 0.6666666666666666
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula: C27H29ClFN5O3
Similarity: 0.6495726495726496
Relative Targets: Epidermal growth factor receptor |