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Approved Drugs
Inhibitors
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula:  C26H27ClFN5O2
Similarity:  0.8715596330275229
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula:  C25H25ClFN5O2
Similarity:  0.8611111111111112
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.8378378378378378
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C23H25ClFN5O3
Similarity:  0.7678571428571429
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula:  C28H29ClFN5O3
Similarity:  0.7398373983739838
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C24H25ClFN5O2
Similarity:  0.7217391304347827
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-methoxypropoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H27ClFN5O3
Similarity:  0.717948717948718
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C26H29ClFN5O3
Similarity:  0.7131147540983607
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C23H23ClFN5O2
Similarity:  0.7105263157894737
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide
Formula:  C25H27ClFN5O4S
Similarity:  0.7016129032258065
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H27ClFN5O3
Similarity:  0.6890756302521008
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-isopropoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C25H29ClFN5O3
Similarity:  0.6776859504132231
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-propoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C25H29ClFN5O3
Similarity:  0.6721311475409836
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H25FN6O3
Similarity:  0.6611570247933884
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula:  C23H23ClFN5O2
Similarity:  0.6610169491525424
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(diethylamino)but-2-enamide
Formula:  C26H31ClFN5O3
Similarity:  0.656
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula:  C22H21ClFN5O2
Similarity:  0.6495726495726496
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H25ClF3N5O3
Similarity:  0.64
Relative Targets:   Epidermal growth factor receptor  |
Name:  Afatinib
Formula:  C24H25ClFN5O3
Similarity:  0.6290322580645161
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |