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Approved Drugs
Inhibitors
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula:  C26H27ClFN5O2
Similarity:  0.8932038834951457
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula:  C27H29ClFN5O3
Similarity:  0.8611111111111112
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C23H23ClFN5O2
Similarity:  0.8235294117647058
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula:  C28H29ClFN5O3
Similarity:  0.7982456140350878
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula:  C22H21ClFN5O2
Similarity:  0.7523809523809524
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C24H25ClFN5O2
Similarity:  0.7339449541284404
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.7105263157894737
Relative Targets:   Epidermal growth factor receptor  |
Name:  Dacomitinib
Formula:  C24H25ClFN5O2
Similarity:  0.6902654867256637
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(diisopropylamino)but-2-enamide
Formula:  C25H29ClFN5O2
Similarity:  0.6814159292035398
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  Afatinib
Formula:  C24H25ClFN5O3
Similarity:  0.6782608695652174
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide
Formula:  C23H23ClFN5O3S
Similarity:  0.6782608695652174
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[(3,3-difluorocyclobutyl)amino]but-2-enamide
Formula:  C23H21ClF3N5O2
Similarity:  0.6754385964912281
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide
Formula:  C18H14ClFN4O2
Similarity:  0.6732673267326733
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-ethoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula:  C23H23ClFN5O2
Similarity:  0.6696428571428571
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula:  C25H25ClFN5O3
Similarity:  0.6554621848739496
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H25ClFN5O3
Similarity:  0.6495726495726496
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C23H25ClFN5O3
Similarity:  0.6434782608695652
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(difluoromethoxy)quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula:  C22H19ClF3N5O2
Similarity:  0.6434782608695652
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1R)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H27ClFN5O3
Similarity:  0.6324786324786325
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |