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Approved Drugs
Inhibitors
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C26H27N5O3
Similarity:  0.8952380952380953
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-[(1-methyl-4-piperidyl)oxy]quinazolin-6-yl]but-2-enamide
Formula:  C28H32N6O2
Similarity:  0.8214285714285714
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide
Formula:  C27H29N5O3
Similarity:  0.7413793103448276
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C27H27N5O3
Similarity:  0.7350427350427351
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-[cyclopropyl(methyl)amino]-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula:  C25H25N5O2
Similarity:  0.7297297297297297
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-[cyclopropyl(methyl)amino]-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula:  C26H27N5O2
Similarity:  0.7105263157894737
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C23H20N4O3
Similarity:  0.7090909090909091
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide
Formula:  C25H27N5O3
Similarity:  0.6956521739130435
Relative Targets:   Epidermal growth factor receptor  |
Name:  Afatinib
Formula:  C24H25ClFN5O3
Similarity:  0.6923076923076923
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |
Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C25H25FN6O3
Similarity:  0.6890756302521008
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C29H31N5O3
Similarity:  0.68
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula:  C24H23N5O2
Similarity:  0.6666666666666666
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H25ClFN5O3
Similarity:  0.6638655462184874
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C25H25ClF3N5O3
Similarity:  0.6532258064516129
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula:  C25H25N5O2
Similarity:  0.6495726495726496
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C26H27N5O2
Similarity:  0.6147540983606558
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C31H31ClFN5O4
Similarity:  0.6086956521739131
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C31H32FN5O4
Similarity:  0.6058394160583942
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C30H31ClN6O4
Similarity:  0.6058394160583942
Relative Targets:   Epidermal growth factor receptor  |