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Approved Drugs
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.8272727272727273
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.5075757575757576
Inhibitors
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.8272727272727273
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Dipeptidyl peptidase 1 |
Name: N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C22H18ClF3N4O3
Similarity: 0.8073394495412844
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H25ClFN5O3
Similarity: 0.7946428571428571
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C25H25FN6O3
Similarity: 0.7586206896551724
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C24H25ClF3N5O3
Similarity: 0.7288135593220338
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula: C26H27N5O3
Similarity: 0.7264957264957265
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C24H24ClF2N5O3
Similarity: 0.6916666666666667
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C24H24ClF2N5O3
Similarity: 0.6916666666666667
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide
Formula: C25H27ClFN5O3
Similarity: 0.6859504132231405
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C31H31ClFN5O4
Similarity: 0.6791044776119403
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C30H31ClN6O4
Similarity: 0.6766917293233082
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[[6-(prop-2-enoylamino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]prop-2-enamide
Formula: C25H22F3N5O4
Similarity: 0.664
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(3,3-difluoroazetidin-1-yl)but-2-enamide
Formula: C25H23ClF3N5O3
Similarity: 0.6587301587301587
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-tetrahydropyran-4-yloxy-quinazolin-6-yl]but-2-enamide
Formula: C27H29N5O3
Similarity: 0.6532258064516129
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide
Formula: C25H25ClFN5O3
Similarity: 0.6532258064516129
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C21H18ClFN4O3
Similarity: 0.6521739130434783
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide
Formula: C28H29ClFN5O3
Similarity: 0.6511627906976745
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula: C31H32FN5O4
Similarity: 0.6397058823529411
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-[4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula: C30H32N6O4
Similarity: 0.625
Relative Targets: Epidermal growth factor receptor |