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Approved Drugs

Name:  Afatinib

Formula:  C24H25ClFN5O3

Similarity:  0.5573770491803278

Inhibitors

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C23H25ClFN5O3

Similarity:  0.7884615384615384

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H25FN6O3

Similarity:  0.7663551401869159

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-methoxypropoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H27ClFN5O3

Similarity:  0.7339449541284404

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide

Formula:  C25H27N5O3

Similarity:  0.7155963302752294

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H25ClF3N5O3

Similarity:  0.7079646017699115

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H27ClFN5O3

Similarity:  0.7027027027027027

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-isopropoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C25H29ClFN5O3

Similarity:  0.6902654867256637

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-propoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C25H29ClFN5O3

Similarity:  0.6842105263157895

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C25H27ClFN5O3

Similarity:  0.6695652173913044

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-4-(dimethylamino)-N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide

Formula:  C30H32FN5O4

Similarity:  0.6377952755905512

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1R)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H27ClFN5O3

Similarity:  0.6347826086956522

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1S)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H27ClFN5O3

Similarity:  0.6347826086956522

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C30H31ClFN5O4

Similarity:  0.627906976744186

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-4-(dimethylamino)-N-[4-[[6-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-7-(2-methoxyethoxy)quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]but-2-enamide

Formula:  C30H36F3N7O4

Similarity:  0.6165413533834586

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C29H31ClN6O4

Similarity:  0.6124031007751938

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide

Formula:  C27H29ClFN5O3

Similarity:  0.6097560975609756

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-4-(dimethylamino)-N-[7-(2-methoxyethoxy)-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]but-2-enamide

Formula:  C29H32N6O4

Similarity:  0.609375

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(diethylamino)but-2-enamide

Formula:  C26H31ClFN5O3

Similarity:  0.5983606557377049

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C31H33N7O3

Similarity:  0.5939849624060151

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |