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Approved Drugs

Name:  Afatinib

Formula:  C24H25ClFN5O3

Similarity:  0.6083333333333333

Name:  Neratinib

Formula:  C30H29ClN6O3

Similarity:  0.5328467153284672

Name:  Dacomitinib

Formula:  C24H25ClFN5O2

Similarity:  0.5158730158730159

Inhibitors

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C23H25ClFN5O3

Similarity:  0.8529411764705882

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-methoxypropoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H27ClFN5O3

Similarity:  0.794392523364486

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C21H18FN5O3

Similarity:  0.7920792079207921

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(4-bromo-2-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C23H25BrFN5O3

Similarity:  0.7663551401869159

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H27ClFN5O3

Similarity:  0.7614678899082569

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide

Formula:  C25H27N5O3

Similarity:  0.7592592592592593

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H25ClF3N5O3

Similarity:  0.75

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-isopropoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C25H29ClFN5O3

Similarity:  0.7477477477477478

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-propoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C25H29ClFN5O3

Similarity:  0.7410714285714286

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C25H27ClFN5O3

Similarity:  0.7256637168141593

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C25H25FN6O3

Similarity:  0.7192982456140351

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1R)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H27ClFN5O3

Similarity:  0.6902654867256637

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(1S)-2-methoxy-1-methyl-ethoxy]quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C24H27ClFN5O3

Similarity:  0.6902654867256637

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C30H31ClFN5O4

Similarity:  0.6640625

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-4-(dimethylamino)-N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide

Formula:  C30H32FN5O4

Similarity:  0.6614173228346457

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide

Formula:  C27H29ClFN5O3

Similarity:  0.6611570247933884

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(diethylamino)but-2-enamide

Formula:  C26H31ClFN5O3

Similarity:  0.65

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C29H31ClN6O4

Similarity:  0.6484375

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C24H23ClFN5O2

Similarity:  0.6347826086956522

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |