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Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.7941176470588235

Name:  Dacomitinib

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.5739130434782609

Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₂H₁₈FN₅O₃

Similarity:  0.8421052631578947

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₂H₁₈ClF₃N₄O₃

Similarity:  0.8080808080808081

Relative Targets:   Epidermal growth factor receptor  |

Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.7941176470588235

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |

Name:  N-[4-(4-bromo-2-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈BrFN₄O₃

Similarity:  0.7731958762886598

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide

Formula:  C₂₅H₂₇ClFN₅O₃

Similarity:  0.7714285714285715

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide

Formula:  C₂₅H₂₅ClFN₅O₃

Similarity:  0.7641509433962265

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.7596153846153846

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₃H₂₀N₄O₃

Similarity:  0.7474747474747475

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₁₈H₁₄ClFN₄O₂

Similarity:  0.7472527472527473

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₃

Similarity:  0.7452830188679245

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₃

Similarity:  0.7452830188679245

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(3,3-difluoroazetidin-1-yl)but-2-enamide

Formula:  C₂₅H₂₃ClF₃N₅O₃

Similarity:  0.7363636363636363

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₈H₂₄ClFN₄O₄

Similarity:  0.7192982456140351

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₂₇H₂₉ClFN₅O₃

Similarity:  0.7168141592920354

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide

Formula:  C₂₈H₂₉ClFN₅O₃

Similarity:  0.7105263157894737

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(4-oxo-1-piperidyl)but-2-enamide

Formula:  C₂₇H₂₇ClFN₅O₄

Similarity:  0.7043478260869566

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C₂₆H₂₇ClFN₅O₄S

Similarity:  0.7043478260869566

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₇H₂₄ClN₅O₄

Similarity:  0.7017543859649122

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-Chloro-4-fluoroanilino)-7-prop-2-ynoxyquinazolin-6-yl]prop-2-enamide

Formula:  C₂₀H₁₄ClFN₄O₂

Similarity:  0.7010309278350515

Relative Targets:   Epidermal growth factor receptor  |