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Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6756756756756757

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈ClFN₄O₃

Similarity:  0.8421052631578947

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₅H₂₅FN₆O₃

Similarity:  0.8

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(4-bromo-2-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈BrFN₄O₃

Similarity:  0.75

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₃H₂₀N₄O₃

Similarity:  0.7425742574257426

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₂H₁₈ClF₃N₄O₃

Similarity:  0.7333333333333333

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈FN₅O₃

Similarity:  0.6893203883495146

Relative Targets:   Epidermal growth factor receptor  |

Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6756756756756757

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |

Name:  N-[4-[[6-(prop-2-enoylamino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]prop-2-enamide

Formula:  C₂₅H₂₂F₃N₅O₄

Similarity:  0.6637931034482759

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide

Formula:  C₂₅H₂₇ClFN₅O₃

Similarity:  0.6578947368421053

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide

Formula:  C₂₅H₂₅ClFN₅O₃

Similarity:  0.6521739130434783

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6460176991150443

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₈H₂₄ClFN₄O₄

Similarity:  0.6446280991735537

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₈H₂₅FN₄O₄

Similarity:  0.6416666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₃

Similarity:  0.6347826086956522

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₃

Similarity:  0.6347826086956522

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(3,3-difluoroazetidin-1-yl)but-2-enamide

Formula:  C₂₅H₂₃ClF₃N₅O₃

Similarity:  0.6302521008403361

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₇H₂₄ClN₅O₄

Similarity:  0.628099173553719

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₁₈H₁₄ClFN₄O₂

Similarity:  0.62

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₂₇H₂₉ClFN₅O₃

Similarity:  0.6147540983606558

Relative Targets:   Epidermal growth factor receptor  |