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Approved Drugs
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.6
Inhibitors
Name: (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula: C26H27N5O3
Similarity: 0.7961165048543689
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide
Formula: C27H29N5O3
Similarity: 0.7735849056603774
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula: C27H27N5O3
Similarity: 0.7663551401869159
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C21H18ClFN4O3
Similarity: 0.7474747474747475
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C22H18FN5O3
Similarity: 0.7425742574257426
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C29H31N5O3
Similarity: 0.7192982456140351
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-tetrahydropyran-4-yloxy-quinazolin-6-yl]but-2-enamide
Formula: C27H29N5O3
Similarity: 0.7090909090909091
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C22H18ClF3N4O3
Similarity: 0.6981132075471698
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(4-bromo-2-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C21H18BrFN4O3
Similarity: 0.696078431372549
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula: C22H20N4O3
Similarity: 0.6831683168316832
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C28H24ClFN4O4
Similarity: 0.6416666666666667
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C28H25FN4O4
Similarity: 0.6386554621848739
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C27H24ClN5O4
Similarity: 0.6386554621848739
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[[6-(prop-2-enoylamino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]prop-2-enamide
Formula: C25H22F3N5O4
Similarity: 0.6324786324786325
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula: C24H23N5O2
Similarity: 0.6296296296296297
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-[(1-methyl-4-piperidyl)oxy]quinazolin-6-yl]but-2-enamide
Formula: C28H32N6O2
Similarity: 0.6239316239316239
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C27H25N5O4
Similarity: 0.6218487394957983
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-[cyclopropyl(methyl)amino]-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula: C25H25N5O2
Similarity: 0.6181818181818182
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(cyclopropylamino)-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula: C25H25N5O2
Similarity: 0.6126126126126126
Relative Targets: Epidermal growth factor receptor |