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Approved Drugs
Inhibitors
Name:  (E)-4-(dimethylamino)-N-[4-[4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C30H32N6O4
Similarity:  0.8278688524590164
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C27H24ClN5O4
Similarity:  0.8135593220338984
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C28H25FN4O4
Similarity:  0.7833333333333333
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C30H31ClN6O4
Similarity:  0.6791044776119403
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C31H32FN5O4
Similarity:  0.6544117647058824
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C28H24ClFN4O4
Similarity:  0.648854961832061
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[7-ethoxy-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula:  C30H32N6O3
Similarity:  0.6370370370370371
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C21H18ClFN4O3
Similarity:  0.6271186440677966
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C23H20N4O3
Similarity:  0.6218487394957983
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[7-ethoxy-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula:  C31H35N7O3
Similarity:  0.6142857142857143
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C22H18FN5O3
Similarity:  0.6115702479338843
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[7-(2-methoxyethoxy)-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]but-2-enamide
Formula:  C29H32N6O4
Similarity:  0.6102941176470589
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C22H18ClF3N4O3
Similarity:  0.592
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(4-bromo-2-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C21H18BrFN4O3
Similarity:  0.5867768595041323
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[7-methoxy-4-[4-(2-pyridylmethyl)anilino]quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula:  C29H30N6O2
Similarity:  0.5467625899280576
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C31H31ClFN5O4
Similarity:  0.54421768707483
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[[6-(prop-2-enoylamino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-4-yl]amino]-2-(trifluoromethyl)phenyl]prop-2-enamide
Formula:  C25H22F3N5O4
Similarity:  0.5441176470588235
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(4-benzyloxyanilino)quinazolin-6-yl]prop-2-enamide
Formula:  C24H20N4O2
Similarity:  0.5396825396825397
Relative Targets:   Epidermal growth factor receptor  |
Name:  Afatinib
Formula:  C24H25ClFN5O3
Similarity:  0.5263157894736842
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |